Document Detail


CRIB (clinical risk index for babies) in relation to nosocomial bacteraemia in very low birthweight or preterm infants.
MedLine Citation:
PMID:  8795357     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Positive blood cultures in very low birthweight or preterm infants usually reflect bacteraemia, septicaemia, or failure of asepsis during sampling and lead to increased costs and length of stay. Rates of nosocomial, or hospital acquired, bacteraemia may therefore be important indicators of neonatal unit performance, if comparisons are adjusted for differences in initial risk. In a preliminary study the risk of nosocomial bacteraemia was related to initial clinical risk and illness severity measured by the clinical risk index for babies (CRIB). Nosocomial bacteraemia was defined as clinically suspected infection with culture of bacteria in blood more than 48 hours after birth. One or more episodes of nosocomial bacteraemia were identified retrospectively in 36 of 143 (25%) infants in a regional neonatal unit between 1992 and 1994. Biologically plausible models were developed using regression analysis techniques. After correcting for period at risk, nosocomial bacteraemia was independently associated with gestation at birth and CRIB. Death was independently associated with CRIB, but not with nosocomial bacteraemia. CRIB may contribute, with other explanatory variables, to more comprehensive predictive models of death and nosocomial infection. These may facilitate future risk adjusted comparative studies between groups of neonatal units.
Authors:
P W Fowlie; C R Gould; G J Parry; G Phillips; W O Tarnow-Mordi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  75     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-10-10     Completed Date:  1996-10-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  F49-52     Citation Subset:  AIM; IM    
Affiliation:
Department of Child Health, Ninewells Hospital and Medical School, University of Dundee.
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MeSH Terms
Descriptor/Qualifier:
Bacteremia / diagnosis*,  mortality
Cohort Studies
Cross Infection / diagnosis*,  mortality
Health Status Indicators*
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / diagnosis*,  mortality
Infant, Very Low Birth Weight*
Length of Stay
Regression Analysis
Retrospective Studies
Risk
Grant Support
ID/Acronym/Agency:
//Wellcome Trust
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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