Document Detail

CPT, the main test method of skin neuronal sensitivity.
MedLine Citation:
PMID:  25198401     Owner:  NLM     Status:  Publisher    
Abstract Background: Many scholars concentrate on skin barrier disruption of sensitive skin, but few focus on its increased neuronal sensitivity. Objective: To study the possibility of using current perception threshold (CPT) measurement for the quantitative evaluation of skin neuronal sensitivity combined with stinging test. Methods: The amount of 50 μL 10% lactic acid was applied on each side of the nasolabial fold at random. Subjects assessed stinging based on a 4-point scale at 30 s, 2.5 min and 5.0 min. CPT and transepidermal water loss (TEWL) were measured before and after stinging test. Subjects were divided into different groups based on their response to lactic acid. Results: There was a positive correlation between CPTbefore and the sum of clinical scores (CSs). While the beginning time of stinging (BT) was shortened, the CPTbefore decreased and TEWL increased. Conclusion: Different degrees of skin susceptibility can be reflected by BT. CPT can be useful for the quantitative evaluation of skin neuronal sensitivity.
Shuyuan Li; Xuemin Wang; Yanrui Gao; Shuangyu Chen; Xiaoping Liu; Haijun Wang; Yaqi Dong
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-8
Journal Detail:
Title:  Cutaneous and ocular toxicology     Volume:  -     ISSN:  1556-9535     ISO Abbreviation:  Cutan Ocul Toxicol     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101266892     Medline TA:  Cutan Ocul Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-4     Citation Subset:  -    
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