Document Detail

CPAP pressure requirements for obstructive sleep apnea patients at varying altitudes.
MedLine Citation:
PMID:  20469814     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVES: This study was performed to determine whether the obstructive sleep apnea patient who requires a certain CPAP pressure at one altitude requires the same or a different CPAP pressure at a different altitude.
PARTICIPANTS: 7 mountain residents with OSA, comfortably using CPAP and planning to travel to lower altitude.
DESIGN AND SETTING: Participants used a ResMed Autoset autotitrating CPAP unit for at least 3 days at their home and at each of their lower travel destinations.
MEASUREMENTS: Nightly CPAP 95th percentile pressure, median CPAP pressure and AHI were recorded.
RESULTS: At high altitude, 7400 ft. to 10,100 ft (2255 m to 3080 m), average CPAP 95th percentile pressure was 9.43 (+/- 0.12) cm H2O. At low altitude, sea level to 2800 ft. (0-853m), average CPAP 95th percentile pressure was 9.54 (+/- 0.13) cm H2O, P = 0.18. At high altitude, median CPAP pressure was 7.00 (+/- 0.10) cm H2O vs. 7.21 (+/- 0.14) cm. H20 at low altitude, P = 0.54. Three patients had a slight decrease in required pressure at low elevation, 4 had a slight increase.
CONCLUSIONS: For obstructive sleep apnea patients living at altitude, changes in elevation between 10,100 ft (3075 m) and sea level do not significantly alter absolute CPAP pressure requirements.
David S Patz; Bruce Swihart; David P White
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sleep     Volume:  33     ISSN:  0161-8105     ISO Abbreviation:  Sleep     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-06-07     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  7809084     Medline TA:  Sleep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  715-8     Citation Subset:  IM    
Department of Medicine, St. Mary's Hospital, Grand Junction, CO, USA.
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MeSH Terms
Continuous Positive Airway Pressure / methods*
Middle Aged
Sleep Apnea, Obstructive / therapy*

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