Document Detail

CPAP Decreases Lung Hyperinflation in Patients With Stable COPD.
MedLine Citation:
PMID:  21496367     Owner:  NLM     Status:  Publisher    
BACKGROUND: As a result of dynamic hyperinflation caused by expiratory flow limitation, resting end-expiratory lung volume (functional residual capacity) is markedly increased in many COPD patients. This investigation aimed at verifying the impact of CPAP on hyperinflation and airway resistance (Raw) in patients with stable COPD, as well as to evaluate the length of these potential beneficial effects. METHODS: In a case series, twenty-one patients underwent an 8 cmH₂O CPAP for 15-min. Whole-body plethysmography was carried out before, immediately after and at 15 and 30 min after the application of CPAP. RESULTS: The mean ± SD age was 70 ± 9 y, and the mean FEV₁ was 40.7 ± 7.9% predicted. Residual volume (RV), FRC, TLC, RV/TLC and Raw decreased after applying CPAP. These values did not change up to 15 min (P < .001), and returned to baseline at 30 min (P > .05). CONCLUSION: In patients with severe-to-very severe stable COPD, CPAP causes reduction in lung volumes and Raw shows lingering effects.
Agnaldo J Lopes; Flávio Nery; Felipe C Sousa; Fernando S Guimarães; Cristina M Dias; Juliana F Oliveira; Sara Menezes
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-15
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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