| COPDX: an update of guidelines for the management of chronic obstructive pulmonary disease with a review of recent evidence. | |
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MedLine Citation:
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PMID: 16584369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Long-acting beta(2) agonists are an effective and convenient treatment for chronic obstructive pulmonary disease (COPD), but do not significantly improve lung function. The long-acting anticholinergic tiotropium, which can be taken once daily, decreases exertional dyspnoea and increases endurance by reducing hyperinflation. The role in COPD of the combination of a long-acting beta(2) agonist and a glucocorticoid in a single inhaler remains unclear. The minimum duration of an effective pulmonary rehabilitation program that includes exercise training is 6 weeks. Long-term treatment with inhaled glucocorticoids may reduce the rate of decline in lung function, but the effect is small. Aminophylline should no longer be routinely used in acute exacerbations of COPD. Non-invasive positive pressure ventilation (NPPV) reduces mortality and hospital stay in patients with acute hypercapnic ventilatory failure; it is also an effective weaning strategy for patients who require intubation. Further studies are required to clarify the role of NPPV in the long-term management of stable COPD. |
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Authors:
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Michael J Abramson; Alan J Crockett; Peter A Frith; Christine F McDonald |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The Medical journal of Australia Volume: 184 ISSN: 0025-729X ISO Abbreviation: Med. J. Aust. Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-04-04 Completed Date: 2006-05-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0400714 Medline TA: Med J Aust Country: Australia |
Other Details:
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Languages: eng Pagination: 342-5 Citation Subset: IM |
Affiliation:
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Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, VIC. michael.abramson@med.monash.edu.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Administration, Oral Adrenergic beta-Agonists / administration & dosage Asthma / diagnosis Australia Bronchodilator Agents / administration & dosage Diagnosis, Differential Drug Combinations Evidence-Based Medicine / methods, standards Expectorants / therapeutic use Glucocorticoids / administration & dosage Humans Practice Guidelines as Topic* Pulmonary Disease, Chronic Obstructive / diagnosis*, therapy* Respiratory Function Tests Risk Factors Scopolamine Derivatives / administration & dosage Social Support Vaccination / standards |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Agonists; 0/Bronchodilator Agents; 0/Drug Combinations; 0/Expectorants; 0/Glucocorticoids; 0/Scopolamine Derivatives; 136310-93-5/tiotropium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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