| COPD pathology in the small airways. | |
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MedLine Citation:
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PMID: 21346704 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In the last quarter of century, the analysis of small airways specimens obtained from chronic obstructive pulmonary disease (COPD) patients compared with those from a control group of age-matched smokers with normal lung function has provided novel insights on the potential role of the different inflammatory and structural cells, pro/anti-inflammatory mediators and intracellular signalling pathways, contributing to a better knowledge of the pathogenesis of stable COPD. This also has provided a scientific rationale for new drugs discovery and targeting to the small airways. This review summarizes and discusses the pathology of small airways of stable COPD patients, of different severity, compared with control smokers with normal lung function. |
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Authors:
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G Caramori; P Casolari; S Giuffrè; A Barczyk; I Adcock; A Papi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Panminerva medica Volume: 53 ISSN: 1827-1898 ISO Abbreviation: Panminerva Med Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0421110 Medline TA: Panminerva Med Country: Italy |
Other Details:
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Languages: eng Pagination: 51-70 Citation Subset: IM |
Affiliation:
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Asthma and COPD Research Center, University of Ferrara, Ferrara, Italy2 Unit of Pneumonology, Medical University of Silesia Katowice, Poland3 Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, UK - gaetano.caramori@unife.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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