Document Detail

COPD Exacerbation: Mortality Prognosis Factors in a Respiratory Care Unit.
MedLine Citation:
PMID:  21316833     Owner:  NLM     Status:  Publisher    
OBJECTIVE: The aim of our study was to investigate the mortality predictive factors after a severe exacerbations of COPD admitted to a Spanish respiratory intermediate care unit (IRCU). PATIENTS AND METHODS: Prospective observational 2 years study, where we included all episodes of acute exacerbations of COPD with hypercapnic respiratory failure admitted in an IRCU. We analyzed different sociodemographic, functional and clinical variables including physical activity. RESULTS: We collected data from 102 consecutive episodes admitted to IRCU (90.1% men). Mean age was 69.4±10.6. The mean APACHE II was 19.6±5.0 and 9.5% presented a failure of other non respiratory organ. Non invasive ventilation was applied in 75.3% of the episodes and this treatment failed in 11.6% of them. The duration of stay in the IRCU was 3.5±2.1 days and 8.0±5.3 days in the hospital. The hospital mortality rate was 6.9%, and another 12.7% after 90 days of discharged. In order to predict hospital mortality, multivariant statistics identified a model with AUC of 0.867, based in 3 variables: the number of previous year admission for COPD exacerbation (p=0,048), the respiratory rate after 2hours of treatment in the IRCU (p=0.0484) and the severity of the disease established with ADO score (p=0.0241). CONCLUSIONS: The number of previous year admission for COPD exacerbation, the severity of the disease established with ADO score, the respiratory rate after 2hours of treatment, allow us to identified what patients with a COPD exacerbation admitted in a IRCU can die during this episode.
Myriam Aburto; Cristóbal Esteban; Francisco Javier Moraza; Urko Aguirre; Mikel Egurrola; Alberto Capelastegui
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-11
Journal Detail:
Title:  Archivos de bronconeumologia     Volume:  -     ISSN:  1579-2129     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0354720     Medline TA:  Arch Bronconeumol     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Espana.
Servicio de Neumología, Hospital de Galdakao, Galdakao, Bizkaia, España.
Vernacular Title:
Exacerbación de EPOC: factores predictores de mortalidad en una unidad de cuidados respiratorios intermedios.
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