| CO2 response for the brain stem artery blood flow velocity in man. | |
| | |
MedLine Citation:
|
PMID: 8865384 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We examined changes in the blood flow velocity of brain stem artery (BSA) and middle cerebral artery (MCA) in response to hypercapnic, normocapnic and hypocapnic hyperventilation in seven awake subjects with a transcranial Doppler to determine if there are differences in blood flow control in regional brain perfused by these respective arteries, and to separate the effects of CO2 and ventilation itself on blood flow velocity during CO2 loading. During hypercapnic hyperventilation, BSA flow velocity increased linearly with an increase in end-tidal partial pressure of CO2 (PETCO2). During hypocapnic hyperventilation, BSA flow velocity decreased linearly with decrease in PETCO2, but did not change during normocapnic hyperventilation. The mean CO2 reactivity of BSA was 2.8%/mmHg. The responses of MCA to these hyperventilations and CO2 reactivity were similar to those of BSA. These findings suggest that CO2 rather than ventilation per se is the important stimulus to changes in brain blood flow velocity and that the CO2 responses of brain arteries are not affected by differences in vascular beds. |
| | |
Authors:
|
W Hida; Y Kikuchi; S Okabe; H Miki; H Kurosawa; K Shirato |
Related Documents
:
|
1523034 - Effect of rapid thoracic compression on the cerebral blood flow-velocity patterns of sm... 22152544 - Developing the evidence base for the new guidelines for reduction of cardiovascular ris... 1874224 - Effect of sub-anaesthetic infusions of propofol on peak velocity of saccadic eye moveme... 6466514 - Use of continuous wave doppler ultrasound velocimetry to assess the severity of coarcta... 10092364 - Electroosmotic flows created by surface defects in capillary electrophoresis. 8048594 - Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric ox... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Respiration physiology Volume: 104 ISSN: 0034-5687 ISO Abbreviation: Respir Physiol Publication Date: 1996 Apr-May |
Date Detail:
|
Created Date: 1997-01-21 Completed Date: 1997-01-21 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0047142 Medline TA: Respir Physiol Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 71-5 Citation Subset: IM |
Affiliation:
|
First Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Flow Velocity Brain Stem / blood supply* Carbon Dioxide / pharmacology* Cerebrovascular Circulation Humans Hypercapnia / physiopathology Hyperventilation / physiopathology Hypocapnia / physiopathology Male Middle Aged |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Respiratory mechanics in the open chest: effects of parietal pleurae.
Next Document: Inositol phosphate turnover in human airways: effect of arachidonic acid metabolism.