Document Detail

CNS involvement in hereditary neuropathy with pressure palsies (HNPP).
MedLine Citation:
PMID:  17190957     Owner:  NLM     Status:  MEDLINE    
We assessed seven patients with hereditary neuropathy with liability to pressure palsies (HNPP) with 16 electrophysiological tests and cranial MRI for CNS abnormalities. Mean latencies differed between patients with HNPP and controls for the blink reflex, the jaw-opening reflex, and acoustic evoked potentials. MRI abnormalities were observed in four patients. Our study suggests subclinical but functionally relevant CNS myelin damage in HNPP.
B Tackenberg; J C Möller; H Rindock; S Bien; N Sommer; W H Oertel; F Rosenow; K Schepelmann; H M Hamer; O Bandmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurology     Volume:  67     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-27     Completed Date:  2007-01-16     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2250-2     Citation Subset:  AIM; IM    
Department of Neurology, Philipps-University, Marburg, Germany.
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MeSH Terms
Brain / pathology*,  physiopathology*
Evoked Potentials
Hereditary Sensory and Motor Neuropathy / pathology*,  physiopathology*
Magnetic Resonance Imaging
Middle Aged
Nerve Fibers, Myelinated / pathology*
Paralysis / pathology*,  physiopathology*
Comment In:
Neurology. 2007 Jun 5;68(23):2046   [PMID:  17548562 ]

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