| CLOVES syndrome with thoracic and central phlebectasia: increased risk of pulmonary embolism. | |
| | |
MedLine Citation:
|
PMID: 20537357 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: CLOVES syndrome (congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal/scoliosis and spinal abnormalities) is a rare, complex overgrowth syndrome with serious morbidity. In this communication we studied the presence of central and thoracic phlebectasia in patients with CLOVES syndrome and its clinical implications. METHODS: We conducted a comprehensive search of our databases at Children's Hospital Boston over the last 10 years (1999-2008) for patients with CLOVES syndrome and central and thoracic phlebectasia. Medical records, clinical photographs, and imaging studies of varying modalities were reviewed. RESULTS: Review of the clinical data and imaging studies of 12 patients with CLOVES syndrome documented the presence of central and thoracic phlebectasia in 11 patients. Two patients had serious perioperative pulmonary embolism, and 1 died. CONCLUSIONS: Central and thoracic phlebectasia in patients with CLOVES syndrome is common and increases the risk of pulmonary embolism. Aggressive prophylactic measures should be considered before major interventions. |
| | |
Authors:
|
Ahmad I Alomari; Patricia E Burrows; Edward Y Lee; Daniel J Hedequist; John B Mulliken; Steven J Fishman |
Related Documents
:
|
16096327 - Beneficial response to anakinra and thalidomide in schnitzler's syndrome. 20845057 - Holmes-adie syndrome associated with high altitude pulmonary edema and low chemo-respon... 3166587 - Electrodiagnostic findings in the early stages of bell's palsy and ramsay-hunt's syndrome. 9179697 - Treatment of crush syndrome patients following the great hanshin earthquake. 15371747 - Selective alteration of native, but not second language articulation in a patient with ... 21123627 - Neurocognitive recovery in smart syndrome: a case report. |
Publication Detail:
|
Type: Journal Article Date: 2010-05-27 |
Journal Detail:
|
Title: The Journal of thoracic and cardiovascular surgery Volume: 140 ISSN: 1097-685X ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-19 Completed Date: 2010-08-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 459-63 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
Division of Vascular and Interventional Radiology, Children's Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA. ahmad.alomari@childrens.harvard.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abnormalities, Multiple* Adolescent Anticoagulants / therapeutic use Boston Child Child, Preschool Databases as Topic Dilatation, Pathologic Female Humans Infant Lipomatosis / congenital*, pathology Male Nevus / congenital*, pathology Phlebography Pulmonary Embolism / etiology*, mortality, pathology, prevention & control Retrospective Studies Risk Assessment Risk Factors Scoliosis / congenital*, pathology Skin Neoplasms / congenital* Spinal Cord / abnormalities* Syndrome Tomography, X-Ray Computed Treatment Outcome Vascular Malformations / complications*, pathology Veins / pathology* Vena Cava Filters |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transp...
Next Document: Increased age is an independent risk factor for radiographic aspiration and laryngeal penetration af...