Document Detail

CKD and sudden cardiac death: epidemiology, mechanisms, and therapeutic approaches.
MedLine Citation:
PMID:  23100219     Owner:  NLM     Status:  MEDLINE    
Multiple studies demonstrate a strong independent association between CKD and cardiovascular events including death, heart failure, and myocardial infarction. This review focuses on recent clinical studies that expand this spectrum of adverse cardiovascular events to include ventricular arrhythmias and sudden cardiac death. In addition, experimental models suggest structural remodeling of the heart and electrophysiologic changes in this population. These processes may explain the increased arrhythmic risk in kidney disease and aid in identifying patients who are at higher risk for sudden cardiac death. Finally, we review here the data to support the use of pharmacologic and device-based therapies for both the primary and secondary prevention of sudden cardiac death.
Isaac R Whitman; Harold I Feldman; Rajat Deo
Related Documents :
8800429 - Comparison of myoglobin, creatine kinase-mb, and cardiac troponin i for diagnosis of ac...
21343159 - Impact of intravenous lidocaine on myocardial injury after off-pump coronary artery sur...
24938629 - Desmoplakin truncations and arrhythmogenic left ventricular cardiomyopathy: characteriz...
24775959 - Clinical implications of intracoronary findings beyond coronary angiograms in patients ...
21456469 - Diagnosis of ischemic heart disease using ck-mb, troponin-i and ischemia modified albumin.
21274719 - Electrical storm originating from a left ventricular epicardial scar in a patient with ...
7706629 - Immediate and long-term survival after intra-aortic balloon pumping: is advanced age an...
15919299 - Coronary endarterectomy: impact on morbidity and mortality when combined with coronary ...
153829 - Asymmetric septal hypertrophy in patients on long-term hemodialysis.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-10-25
Journal Detail:
Title:  Journal of the American Society of Nephrology : JASN     Volume:  23     ISSN:  1533-3450     ISO Abbreviation:  J. Am. Soc. Nephrol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  2013-02-04     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  9013836     Medline TA:  J Am Soc Nephrol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1929-39     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Death, Sudden, Cardiac / epidemiology,  etiology,  prevention & control*
Defibrillators, Implantable
Renal Insufficiency, Chronic / complications*,  drug therapy,  epidemiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Mechanisms and Treatment of CKD.
Next Document:  NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury.