Document Detail

CD5+ persistent polyclonal B-cell lymphocytosis in a male.
MedLine Citation:
PMID:  10342588     Owner:  NLM     Status:  MEDLINE    
Persistent polyclonal B-cell lymphocytosis with binucleate lymphocytes is a rare lymphoproliferative syndrome of uncertain cause that is strongly associated with HLA-DR7 positivity, cigarette smoking, and female sex. As yet, there is no explanation for the strong sex predilection. We report the third case of persistent polyclonal B-cell lymphocytosis in a male. Other notable findings in this case are lack of HLA-DR7 and strong positive CD5 markers in the polyclonal B-cell population. To our knowledge, CD5 expression has not been mentioned or reported in association with this syndrome.
C B Reeder; C R Conley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Leukemia & lymphoma     Volume:  33     ISSN:  1042-8194     ISO Abbreviation:  Leuk. Lymphoma     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-07-12     Completed Date:  1999-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9007422     Medline TA:  Leuk Lymphoma     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  593-6     Citation Subset:  IM    
Department of Laboratory Medicine and Pathology, Mayo Clinic Scottsdale, Arizona 85259, USA.
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MeSH Terms
Antigens, CD5
B-Lymphocytes / immunology,  pathology*
Cell Differentiation
Lymphoproliferative Disorders / immunology,  pathology
Reg. No./Substance:
0/Antigens, CD5

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