Document Detail

CD4+ lymphocytopenia due to common variable immunodeficiency mimicking AIDS.
MedLine Citation:
PMID:  8027379     Owner:  NLM     Status:  MEDLINE    
There are an increasing number of published reports of patients with acquired immunodeficiency without evidence of HIV infection, who have been labelled as having "idiopathic CD4+ lymphocytopenia". The case is reported here of a young man who presented with Pneumocystis carinii pneumonia (PCP), CD4+ lymphopenia, and hypogammaglobulinaemia attributable to common variable immunodeficiency (CVID). The presentation of this condition, with many of the clinical and laboratory features of AIDS, highlights CVID as a diagnosis to be considered in the differential diagnosis of CD4+ lymphocytopenia.
R S Kaczmarski; A D Webster; J Moxham; F Davison; S Sutherland; G J Mufti
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  47     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1994 Apr 
Date Detail:
Created Date:  1994-08-08     Completed Date:  1994-08-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  364-6     Citation Subset:  AIM; IM; X    
Department of Haematological Medicine, King's College School of Medicine and Dentistry, London.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications*
Common Variable Immunodeficiency / complications*,  therapy
Diagnosis, Differential
Immunoglobulins / therapeutic use
Pneumonia, Pneumocystis / complications
T-Lymphocytopenia, Idiopathic CD4-Positive / etiology*
Reg. No./Substance:

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