Document Detail


A (CA)n repeat polymorphism for the human skeletal muscle alpha-actinin gene ACTN2 and its localization on the linkage map of chromosome 1.
MedLine Citation:
PMID:  1505962     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A CA dinucleotide repeat polymorphism has been identified for the skeletal muscle alpha-actinin gene ACTN2. The observed heterozygosity is 44% (predicted heterozygosity 50%, PIC 0.47). This polymorphic marker has been localized between D1S74 and D1S103 on the multipoint linkage map of chromosome 1 at a position 44.4 cM from the most distal marker D1S68 at 1 qter.
Authors:
A H Beggs; H A Phillips; H Kozman; J C Mulley; S D Wilton; L M Kunkel; N G Laing
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Genomics     Volume:  13     ISSN:  0888-7543     ISO Abbreviation:  Genomics     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-22     Completed Date:  1992-09-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8800135     Medline TA:  Genomics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1314-5     Citation Subset:  IM    
Affiliation:
Genetics Division, Children's Hospital, Boston, Massachusetts 02115.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Actinin / genetics*
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 1*
DNA
Heterozygote
Humans
Linkage (Genetics)*
Molecular Sequence Data
Muscles / metabolism*
Polymorphism, Genetic*
Repetitive Sequences, Nucleic Acid
Chemical
Reg. No./Substance:
11003-00-2/Actinin; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Structure and sequence of the human alpha-L-iduronidase gene.
Next Document:  NF1-related locus on chromosome 15.