Document Detail


CAT scan and immunohistochemical findings in a case of cerebral thromboangiitis obliterans (Buerger's disease).
MedLine Citation:
PMID:  6714279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunohistochemical examinations were carried out in a case of thromboangiitis obliterans. A 26-year-old man developed 4 brain infarctions which could be demonstrated by CAT scan. He suffered from a left-sided hemiparesis, major epileptic seizures, and an ischemic optic neuritis. Immunologic studies supported a diagnosis of cerebral thromboangiitis obliterans (CTAO). The serum anti-elastin titer as well as IgE were considerably increased and a biopsy of the temporal artery showed immunohistochemical signs of an acute inflammatory vessel disease. After the diagnosis of CTAO had been made, the patient was treated with azathioprine and dexamethasone. In cases of young stroke patients, a temporal biopsy is important in confirming the diagnosis.
Authors:
C Kessler; R Reuther; P Berlit; C Carls; W Hofmann
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European neurology     Volume:  23     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1984  
Date Detail:
Created Date:  1984-05-30     Completed Date:  1984-05-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  7-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / pathology,  radiography
Cerebral Infarction / immunology*
Diagnosis, Differential
Epilepsy / etiology
Hemiplegia / etiology
Humans
Immunoglobulin E / analysis
Male
Optic Neuritis / etiology
Temporal Arteries / immunology
Thromboangiitis Obliterans / complications,  diagnosis,  immunology*,  pathology
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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