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CASE REPORT Febrile Ulceronecrotic Mucha-Habermann Disease.
MedLine Citation:
PMID:  20697454     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective: Case report and review of the current literature about febrile ulceronecrotic Mucha-Habermann disease (FUMHD). Methods: Review of our patient's medical records and of the current literature. Results: The FUMHD is a rare and potentially lethal type of pityriasis lichenoides et varioliformis acuta. It is characterized by the sudden onset of ulceronecrotic skin lesions associated with high fever and systemic symptoms. Because of a high case-fatality rate it requires quick and decisive action. Only 40 cases of this severe form of the disease have been reported in the literature to date. We present the case of a 30-year-old male patient with severe FUMHD who was successfully treated in our burn intensive care unit after failed treatment at a dermatological hospital. The patient was treated with topical antiseptics, moisturizers, and artificial skin substitutes, as well as systemic immunosuppressive therapy (glucocorticoids) with which we were able to control the disease activity so that healing of the patient's skin lesions could be achieved. Conclusion: Patients with FUMHD should be treated in a specialized center for severely burned patients. Only such centers can provide the structural and logistical capacities necessary for the treatment of such extensive superficial wounds.
Authors:
Patrick S Harenberg; Manuel Hrabowski; Henning Ryssel; Emre Gazyakan; Günter Germann; Holger Engel; Matthias A Reichenberger
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Publication Detail:
Type:  Journal Article     Date:  2010-07-16
Journal Detail:
Title:  Eplasty     Volume:  10     ISSN:  1937-5719     ISO Abbreviation:  Eplasty     Publication Date:  2010  
Date Detail:
Created Date:  2010-08-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316107     Medline TA:  Eplasty     Country:  United States    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Hand, Plastic, and Reconstructive Surgery Burn Center; BG Trauma Center Ludwigshafen, Department of Plastic and Hand Surgery, University of Heidelberg, Ludwig-Guttmann, Ludwigshafen, Germany.
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