| CALHM1 P86L Polymorphism is a Risk Factor for Alzheimer's Disease in the Chinese Population. | |
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MedLine Citation:
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PMID: 19749425 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We conducted a case-control study to determine the prevalence of CALHM1 P86L polymorphism (rs2986017) in patients with Alzheimer's disease (AD) in the Chinese population of mainland China, and also to clarify whether this polymorphism is a risk factor for AD. Fourteen heterozygous P86L carriers were identified among 198 AD patients. One control subject was also found to be a P86L heterozygous carrier. The allelic frequencies of the AD patients and control subjects were found to be significantly different. Our study indicates that the CALHM1-P86L polymorphism is associated with AD in the ethnic Chinese Han. |
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Authors:
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Pei-Jing Cui; Lan Zheng; Li Cao; Ying Wang; Yu-Lei Deng; Gang Wang; Wei Xu; Hui-Dong Tang; Jian-Fang Ma; Ting Zhang; Jian-Qing Ding; Qi Cheng; Sheng-Di Chen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2009-9-11 |
Journal Detail:
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Title: Journal of Alzheimer's disease : JAD Volume: - ISSN: 1875-8908 ISO Abbreviation: J. Alzheimers Dis. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-9-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9814863 Medline TA: J Alzheimers Dis Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated to the Shanghai Jiaotong University School of Medicine, Shanghai, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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