Document Detail

CA-125 ovarian cancer associated antigen in cancer and pregnancy: interpretation of enzyme immunoassay and immunoradiometric assay.
MedLine Citation:
PMID:  2697189     Owner:  NLM     Status:  MEDLINE    
Serum CA-125 concentrations were determined using both immunoradiometric assay (IRMA) and enzyme immunoassay (EIA) in 67 patients with various diseases including cancer and in 100 pregnant women with respect to the stage of pregnancy. Correlation of values obtained by the two methods was good except for the first and second trimester of pregnancy. However, IRMA concentrations were 80-200% higher than those obtained by EIA, the larger differences being observed in the critical range of 35-100 U/mL. Therefore, the alternate use of the two methods should be avoided and the cutoff levels should be redefined for each procedure.
Y Touitou; A Bogdan; Y Darbois
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anticancer research     Volume:  9     ISSN:  0250-7005     ISO Abbreviation:  Anticancer Res.     Publication Date:    1989 Nov-Dec
Date Detail:
Created Date:  1990-04-12     Completed Date:  1990-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  GREECE    
Other Details:
Languages:  eng     Pagination:  1805-7     Citation Subset:  IM    
Department of Biochemistry, Faculté de Médecine Pittié-Salpêtrière, Paris, France.
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MeSH Terms
Antigens, Tumor-Associated, Carbohydrate / analysis*
Breast Neoplasms / blood
Colonic Neoplasms / blood
Immunoenzyme Techniques
Neoplasms / blood*
Ovarian Neoplasms / blood*
Pregnancy / blood*
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Reg. No./Substance:
0/Antigens, Tumor-Associated, Carbohydrate

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