| C1q nephropathy in the pediatric population: pathology and pathogenesis. | |
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MedLine Citation:
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PMID: 20180137 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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C1q nephropathy was originally described nearly 25 years ago by Jennette and Hipp. Since that time there have been a limited number of publications on C1q nephropathy, most of them in the pediatric literature. Despite reported incidences as high as 16% in some pediatric biopsy series, a consensus definition on the diagnosis of C1q nephropathy is lacking and its existence as a distinct clinical disease entity remains controversial. The purpose of this review is to discuss the biology of C1q in the context of mechanisms of C1q deposition, and to provide a detailed analysis of the published pediatric case series with a focus on the pathological criteria used to establish the diagnosis of C1q nephropathy as well as long-term outcomes in children. |
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Authors:
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Scott E Wenderfer; Rita D Swinford; Michael C Braun |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-02-24 |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 25 ISSN: 1432-198X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-06-18 Completed Date: 2010-10-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 1385-96 Citation Subset: IM |
Affiliation:
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Division of Pediatric Nephrology and Hypertension, Department of Pediatrics, University of Texas School of Medicine, Houston, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Child Chronic Disease Glomerulonephritis / diagnosis*, pathology* Humans Kidney Diseases / pathology* Population Groups |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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