| C1 inactivator and C3b inactivator in peripheral lymph of normal men. | |
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MedLine Citation:
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PMID: 7149928 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The concentrations of C1 inactivator and C3b inactivator were measured in the peripheral lymph of leg of normal men and compared with the concentrations in serum. Both inactivators were found in lymph, however, in concentrations lower than in serum (lymph/serum ratio for C1INA 0.236, for C3bINA 0.238). The levels of C1INA proteins in lymph were higher than of C1q and C1s (p less than 0.05), and of C3bINA higher or equal to those of C3 and C3PA. This may indicate, that the relatively high concentrations of both inactivators in the extravascular space, as compared with complement component proteins, can play a role in the control of activation process of complement in the interstitium and also explain to some extent the observed low hemolytic activity of lymph C1 and C3. |
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Authors:
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W L Olszewski; B Lukomska; A Engeset |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archivum immunologiae et therapiae experimentalis Volume: 30 ISSN: 0004-069X ISO Abbreviation: Arch. Immunol. Ther. Exp. (Warsz.) Publication Date: 1982 |
Date Detail:
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Created Date: 1983-01-19 Completed Date: 1983-01-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0114365 Medline TA: Arch Immunol Ther Exp (Warsz) Country: POLAND |
Other Details:
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Languages: eng Pagination: 79-86 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Complement C1 Inactivator Proteins / metabolism* Complement C3b Inactivator Proteins / metabolism* Extracellular Space / immunology Hemolysis Humans Lymph / immunology* Male |
| Chemical | |
Reg. No./Substance:
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0/Complement C1 Inactivator Proteins; 0/Complement C3b Inactivator Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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