Document Detail

Is C-reactive protein useful in the management of children with suspected bacterial meningitis?
MedLine Citation:
PMID:  6731357     Owner:  NLM     Status:  MEDLINE    
C-reactive protein (CRP) was evaluated in both serum and cerebrospinal fluid in 119 patients to determine if either or both measurements were of clinical value in the diagnosis of bacterial meningitis. CSF C-reactive protein is too insensitive (sensitivity = 66%) to be useful, while serum CRP is too nonspecific for routine application. Serum CRP may have a role if used selectively in those patients with a low-grade CSF pleocytosis and a negative Gram's stain.
D R Benjamin; K E Opheim; L Brewer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  81     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-07-09     Completed Date:  1984-07-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  779-82     Citation Subset:  AIM; IM    
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MeSH Terms
C-Reactive Protein / analysis*,  cerebrospinal fluid
Child, Preschool
Infant, Newborn
Meningitis / blood,  cerebrospinal fluid,  diagnosis*
Meningitis, Aseptic / blood,  cerebrospinal fluid,  diagnosis
Reg. No./Substance:
9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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