| C-reactive protein and other inflammatory biomarkers as predictors of outcome following acute coronary syndromes. | |
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MedLine Citation:
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PMID: 15199444 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite diagnostic and therapeutic advances, the rate of event recurrence is still relatively high and short- and long-term prediction of risk is necessary although extremely challenging to provide optimal treatment to patients with acute coronary syndromes. Available data recommend the use of C-reactive protein (CRP) as a prognostic marker in patients with acute coronary syndromes in addition to other prognostic factors including troponin levels. Evaluation of CRP levels at time of admission should be included in the evaluation of the patient's risk profile, including clinical data, associated diseases, markers of myocardial necrosis (especially troponin levels), left ventricle performance, and age. A cutoff level of 10 mg/L for CRP may be used as a marker of higher risk for death and possibly myocardial infarction in acute coronary syndromes, and a cutoff of 3 mg/L identifies a group of patients with intermediate risk and a high rate of recurrent events. |
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Authors:
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Antonio Abbate; Giuseppe G L Biondi-Zoccai; Salvatore Brugaletta; Giovanna Liuzzo; Luigi M Biasucci |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in vascular medicine Volume: 3 ISSN: 1528-9648 ISO Abbreviation: Semin Vasc Med Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2004-06-16 Completed Date: 2004-07-29 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100940307 Medline TA: Semin Vasc Med Country: United States |
Other Details:
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Languages: eng Pagination: 375-84 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Medicine, Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angina, Unstable
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diagnosis*,
therapy Biological Markers / blood C-Reactive Protein / metabolism* Humans Inflammation / diagnosis*, therapy Myocardial Infarction / diagnosis*, therapy Predictive Value of Tests Prognosis Recurrence Risk Assessment Syndrome Troponin / blood |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Troponin; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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