Document Detail

C-reactive protein and other inflammatory biomarkers as predictors of outcome following acute coronary syndromes.
MedLine Citation:
PMID:  15199444     Owner:  NLM     Status:  MEDLINE    
Despite diagnostic and therapeutic advances, the rate of event recurrence is still relatively high and short- and long-term prediction of risk is necessary although extremely challenging to provide optimal treatment to patients with acute coronary syndromes. Available data recommend the use of C-reactive protein (CRP) as a prognostic marker in patients with acute coronary syndromes in addition to other prognostic factors including troponin levels. Evaluation of CRP levels at time of admission should be included in the evaluation of the patient's risk profile, including clinical data, associated diseases, markers of myocardial necrosis (especially troponin levels), left ventricle performance, and age. A cutoff level of 10 mg/L for CRP may be used as a marker of higher risk for death and possibly myocardial infarction in acute coronary syndromes, and a cutoff of 3 mg/L identifies a group of patients with intermediate risk and a high rate of recurrent events.
Antonio Abbate; Giuseppe G L Biondi-Zoccai; Salvatore Brugaletta; Giovanna Liuzzo; Luigi M Biasucci
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in vascular medicine     Volume:  3     ISSN:  1528-9648     ISO Abbreviation:  Semin Vasc Med     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2004-06-16     Completed Date:  2004-07-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100940307     Medline TA:  Semin Vasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  375-84     Citation Subset:  IM    
Department of Cardiovascular Medicine, Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy.
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MeSH Terms
Angina, Unstable / diagnosis*,  therapy
Biological Markers / blood
C-Reactive Protein / metabolism*
Inflammation / diagnosis*,  therapy
Myocardial Infarction / diagnosis*,  therapy
Predictive Value of Tests
Risk Assessment
Troponin / blood
Reg. No./Substance:
0/Biological Markers; 0/Troponin; 9007-41-4/C-Reactive Protein

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