Document Detail


C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis.
MedLine Citation:
PMID:  18535598     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors.
METHODS: CRP levels in 16 patients with RAO were compared with levels in 16 age-matched controls at risk of atherosclerosis and 16 young volunteers. Repeated CRP testing was performed 6 years later.
RESULTS: Elevated CRP levels (>3 mg/l) and risk factors for atherosclerosis were detected in seven patients in the study group (44%) and nine at-risk controls (56%). On follow-up, CRP levels were reduced in all seven retested patients. Six patients died of vascular events within 5 years, of whom four had high CRP levels during RAO.
CONCLUSIONS: CRP level correlates with atherosclerosis but it is not significantly elevated in patients with RAO.
Authors:
N Goldenberg-Cohen; Y Cohen; Y Monselise; I Eldar; R Axer-Siegel; D Weinberger; M Kramer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-06-06
Journal Detail:
Title:  Eye (London, England)     Volume:  23     ISSN:  1476-5454     ISO Abbreviation:  Eye (Lond)     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-16     Completed Date:  2011-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  785-90     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqwa, Israel. ncohen1@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Aged, 80 and over
Atherosclerosis / blood*,  diagnosis,  mortality
Biological Markers / blood
C-Reactive Protein / analysis*
Carotid Arteries / ultrasonography
Case-Control Studies
Echocardiography, Doppler
Female
Humans
Male
Middle Aged
Retinal Artery Occlusion / blood*
Risk Factors
Young Adult
Chemical
Reg. No./Substance:
0/Biological Markers; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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