Document Detail


C-reactive protein in CNS infection.
MedLine Citation:
PMID:  1797668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum and CSF levels of CRP were measured by radial immunoassay in 99 subjects consisting of 20 controls, 34 pyogenic meningitis (PM), 21 tuberculous meningitis (TBM) and 24 viral encephalitis (VE). There was significant difference in the CRP levels (p less than 0.01) depending on the type of disease in both serum and CSF. The initial serum and CSF levels of CRP in patients with TBM was intermediate between those of PM and VE and were found to be significantly (p less than 0.001) low when compared with three days post treatment levels in children with PM. Both serum and CSF-CRP levels were significantly high (p less than 0.001) in patients succumbing to death than those who survived. Measurement of CRP in serum and CSF is a useful parameter in differentiating partially treated PM from TBM.
Authors:
P Ahmad; S M Ali; S Fakhir; J Chandra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian pediatrics     Volume:  28     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-04-13     Completed Date:  1992-04-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  1167-70     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, J.N. Medical College, A.M.U., Aligarh.
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MeSH Terms
Descriptor/Qualifier:
Biological Markers / blood,  cerebrospinal fluid
C-Reactive Protein / metabolism*
Central Nervous System Diseases / metabolism,  mortality
Child
Child, Preschool
Encephalitis, Arbovirus / metabolism*,  mortality
Humans
Infant
Meningitis / metabolism*,  mortality
Tuberculosis, Meningeal / metabolism*,  mortality
Chemical
Reg. No./Substance:
0/Biological Markers; 9007-41-4/C-Reactive Protein

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