Document Detail

C-reactive protein, fibrinogen, and cardiovascular risk.
MedLine Citation:
PMID:  23281989     Owner:  NLM     Status:  In-Data-Review    
To the Editor: Kaptoge and colleagues (Oct. 4 issue)(1) suggest that C-reactive protein (CRP) and fibrinogen, two biomarkers of inflammation, have a significant though limited incremental prognostic value when added to conventional risk factors. However, the implied ordering of risk factors on the basis of the chronology of their identification as risk factors should be challenged and replaced by an ordering that is based on their effect on prognostic accuracy. The hazard ratios for cardiovascular events (Table 1 of the article) for CRP or fibrinogen levels are in the range of those for established lipid risk factors and even blood . . .
Thomas M Stulnig
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  368     ISSN:  1533-4406     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-6     Citation Subset:  AIM; IM    
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