Document Detail

C-reactive protein as a detector of organic complications during recovery from childhood purulent meningitis.
MedLine Citation:
PMID:  6726518     Owner:  NLM     Status:  MEDLINE    
Twenty-eight bacteriologically proved episodes of purulent meningitis in 27 infants and children were monitored prospectively with sequential determinations of serum C-reactive protein. Except in one rapidly fatal case, all the patients showed decreasing CRP values for about 1 week. In five patients the CRP values than returned to a high level (P less than 0.001). Each of these patients developed an organic complication (subdural effusions in three, transient widening of the ventricles in one, purulent arthritis with osteomyelitis in one). Except for one infant with sensorineural hearing loss, which probably had developed early in the course of meningitis, no permanent sequelae were found in the patients with uncomplicated courses. One infant later had a relapse of Escherichia coli meningitis, reflected in a sharp increase of CRP. We conclude that sequential CRP measurements may be performed routinely to detect potential complications at an early stage of bacterial meningitis.
H Peltola; K Luhtala; P Valmari
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  104     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-07-09     Completed Date:  1984-07-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  869-72     Citation Subset:  AIM; IM    
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MeSH Terms
Arthritis, Infectious / diagnosis
Bacterial Infections / diagnosis*
C-Reactive Protein / analysis*
Child, Preschool
Follow-Up Studies
Infant, Newborn
Meningitis / complications*,  diagnosis
Osteomyelitis / diagnosis
Subdural Effusion / microbiology
Reg. No./Substance:
9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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