Document Detail


Buschke-Ollendorff syndrome.
MedLine Citation:
PMID:  18986450     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Buschke-Ollendorff syndrome is a rare autosomal dominant disease featuring osteopoikilosis and skin lesions. It is caused by genetic mutations in a protein deeply involved in bone and connective tissue morphogenesis. METHODS: We describe a 39-year-old woman with Buschke-Ollendorff syndrome. RESULTS: After a minor trauma, radiologic examination of the left ankle of a 39-year-old woman revealed features of osteopoikilosis. Physical examination of the patient showed multiple asymptomatic nodules on both thighs, present since the age of 20 years, which had increased in size and number. Recently, a linear, string-like lesion had appeared on the right thigh. CONCLUSION: The correct diagnosis of Buschke-Ollendorff syndrome may require a high index of suspicion.
Authors:
Donatella Schena; Lerica Germi; Maria Rosa Zamperetti; Chiara Colato; Giampiero Girolomoni
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  47     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-06     Completed Date:  2009-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1159-61     Citation Subset:  IM    
Affiliation:
Department of Biomedical and Surgical Sciences, Section of Dermatology and Venereology, University of Verona, Verona, Italy. donatella.schena@azosp.vr.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Leg Dermatoses / diagnosis*,  pathology
Osteopoikilosis / diagnosis*,  pathology
Skin / pathology
Skin Diseases, Genetic / diagnosis*,  pathology
Syndrome

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