Document Detail


Burning mouth syndrome responsive to pramipexol.
MedLine Citation:
PMID:  18219443     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Burning mouth syndrome (BMS) is characterized by burning discomfort or pain in otherwise normal oral mucosa. It is usually refractory. Treatment modalities are scarce. Herein we report one case of primary disabling BMS, previously refractory to multiple regimens, with complete and persistent improvement with pramipexol, a nonergot dopamine agonist which has high selectivity for dopaminergic D2 receptors. We discuss potential pathophysiological implications of our findings.
Authors:
J Stuginski-Barbosa; G G R Rodrigues; M E Bigal; J G Speciali
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-01-25
Journal Detail:
Title:  The journal of headache and pain     Volume:  9     ISSN:  1129-2369     ISO Abbreviation:  J Headache Pain     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-18     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100940562     Medline TA:  J Headache Pain     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  43-5     Citation Subset:  IM    
Affiliation:
The Department of Neurology, School of Medicine at Ribeirão Preto, Ribeirão Preto, SP, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Aged
Benzothiazoles / administration & dosage*
Burning Mouth Syndrome / drug therapy*,  metabolism,  physiopathology
Corpus Striatum / drug effects,  metabolism,  physiopathology
Dopamine / metabolism
Dopamine Agonists / administration & dosage*
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Resistance / drug effects,  physiology
Female
Humans
Mouth Mucosa / drug effects*,  innervation,  physiopathology
Parkinson Disease / complications,  drug therapy,  physiopathology
Prospective Studies
Receptors, Dopamine D2 / agonists*,  metabolism
Restless Legs Syndrome / drug therapy,  physiopathology
Substance Withdrawal Syndrome / physiopathology
Treatment Outcome
Chemical
Reg. No./Substance:
0/Benzothiazoles; 0/Dopamine Agonists; 0/Receptors, Dopamine D2; 104632-26-0/pramipexol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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