| Burn severity and post-burn infertility in men. | |
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MedLine Citation:
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PMID: 19765905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Burn wounds are a common cause of much morbidity and misery, especially in low- and medium-income countries. A number of studies show that severe burns cause infertility from poor sperm production. The pathways leading to such infertility are not well understood, and it is not known how the severity of injury affects this post-burn infertility (PBI). We evaluated the relationship between sperm parameters and indices of burn severity, such as burn surface area and depth in 19 adults. Total sperm counts ranged from 0 to 160 million/ml, with a mean of 19.58+/-7.52 million/ml. About 60% of the subjects had total counts of 20 million/ml or less, falling into the clinically oligospermic range. We found only a weak correlation between infertility and both burn depth and burn surface area. There was, however, a fairly strong positive correlation between infertility and length of time between injury and participation in the study. The correlation coefficient was 0.560. Our findings suggest that PBI is progressive and not predicted by TBSA. Any measures to control it should be started early and be applied to burn patients across a wide range of clinical severity. |
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Authors:
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I O Fadeyibi; P I Jewo; L C Saalu; O I Akinola; O Fabamwo; S A Ademiluyi |
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Publication Detail:
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Type: Journal Article Date: 2009-09-18 |
Journal Detail:
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Title: Burns : journal of the International Society for Burn Injuries Volume: 36 ISSN: 1879-1409 ISO Abbreviation: Burns Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-03-15 Completed Date: 2010-10-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8913178 Medline TA: Burns Country: Netherlands |
Other Details:
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Languages: eng Pagination: 367-71 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd and ISBI. All rights reserved. |
Affiliation:
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Department of Plastic Surgery, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Burns / complications*, pathology Disease Progression Follow-Up Studies Humans Infertility, Male / etiology*, physiopathology Male Middle Aged Prospective Studies Sperm Count Sperm Motility |
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