Document Detail

Burn severity and post-burn infertility in men.
MedLine Citation:
PMID:  19765905     Owner:  NLM     Status:  MEDLINE    
Burn wounds are a common cause of much morbidity and misery, especially in low- and medium-income countries. A number of studies show that severe burns cause infertility from poor sperm production. The pathways leading to such infertility are not well understood, and it is not known how the severity of injury affects this post-burn infertility (PBI). We evaluated the relationship between sperm parameters and indices of burn severity, such as burn surface area and depth in 19 adults. Total sperm counts ranged from 0 to 160 million/ml, with a mean of 19.58+/-7.52 million/ml. About 60% of the subjects had total counts of 20 million/ml or less, falling into the clinically oligospermic range. We found only a weak correlation between infertility and both burn depth and burn surface area. There was, however, a fairly strong positive correlation between infertility and length of time between injury and participation in the study. The correlation coefficient was 0.560. Our findings suggest that PBI is progressive and not predicted by TBSA. Any measures to control it should be started early and be applied to burn patients across a wide range of clinical severity.
I O Fadeyibi; P I Jewo; L C Saalu; O I Akinola; O Fabamwo; S A Ademiluyi
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Publication Detail:
Type:  Journal Article     Date:  2009-09-18
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  36     ISSN:  1879-1409     ISO Abbreviation:  Burns     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-03-15     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd and ISBI. All rights reserved.
Department of Plastic Surgery, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
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MeSH Terms
Burns / complications*,  pathology
Disease Progression
Follow-Up Studies
Infertility, Male / etiology*,  physiopathology
Middle Aged
Prospective Studies
Sperm Count
Sperm Motility

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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