Document Detail

Burn healing is dependent on burn site: a quantitative analysis from a porcine burn model.
MedLine Citation:
PMID:  18845398     Owner:  NLM     Status:  MEDLINE    
This retrospective review examines healing in different sites on a porcine burn model; 24 pairs of burns on 18 pigs from other animal trials were selected for analysis. Each pair of burns was located on the either the cranial or the caudal part of the thoracic ribs region, on the same side of the animal. The burns were 40-50 cm(2) in size and of uniform deep-dermal partial thickness. Caudal burns healed significantly better than cranial burns, demonstrated by earlier closure of wounds, less scar formation and better cosmesis. To our knowledge, this is the first detailed study reporting that burn healing is affected by location on a porcine burn model. We recommend that similar symmetrical burns should be used for future comparative assessments of burn healing.
Xue-Qing Wang; Pei-Yun Liu; Margit Kempf; Leila Cuttle; Allen Hong-En Chang; Michael Wong; Olena Kravchuk; Julie Mill; Roy M Kimble
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-10-08
Journal Detail:
Title:  Burns : journal of the International Society for Burn Injuries     Volume:  35     ISSN:  1879-1409     ISO Abbreviation:  Burns     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-03     Completed Date:  2009-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913178     Medline TA:  Burns     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  264-9     Citation Subset:  IM    
Department of Paediatrics and Child Health, University of Queensland, Royal Children's Hospital, Brisbane 4029, Australia.
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MeSH Terms
Burns / physiopathology*
Cicatrix / physiopathology*
Models, Animal
Skin / injuries,  physiopathology*
Thoracic Injuries / physiopathology*
Wound Healing / physiology*

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