Document Detail


Burkitt's lymphoma of the scapula.
MedLine Citation:
PMID:  14692223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Burkitt's lymphoma may involve the maxilla or mandible, but to date, there has been no reference in the literature to scapular involvement by this tumor. This article describes the case of a 9-year-old child who presented with a huge tumor involving the right shoulder with osteolytic and sclerotic lesions in the scapula. The histopathological findings were suggestive of Burkitt's lymphoma, and the immunohistochemical findings discard a lymphoblastic lymphoma or plasmablastic lymphoma. In addition, in situ hybridization for Epstein-Barr virus encoded small nuclear RNA (EBER) was positive. Although the child also presented a cervical lymphadenopathy, the fact that Burkitt's lymphoma is generally extranodal, the marked swelling of the shoulder, and the extensive involvement of the bone strongly argue that this tumor had its origin in the scapula. This case demonstrates the importance of including Burkitt's lymphoma in the differential diagnosis of lymphoma involving bones in children.
Authors:
Achiléa L Bittencourt; Iguaracyra Araujo; Eni G Carvalho; Maria das Graças S Vieira; Michael Hummel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric pathology & molecular medicine     Volume:  22     ISSN:  1522-7952     ISO Abbreviation:  Pediatr Pathol Mol Med     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-12-24     Completed Date:  2004-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100885435     Medline TA:  Pediatr Pathol Mol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271-6     Citation Subset:  IM    
Affiliation:
Department of Pathology, Hospital Universitário Prof. Edgard Santos, Federal University of Bahia, Pediatric Oncology, Hospital Santa Isabel, Salvador, Bahia, Brazil. achilea@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group
Antineoplastic Agents / therapeutic use
Biopsy
Bone Neoplasms / diagnosis,  immunology,  pathology*,  radiography,  virology*
Burkitt Lymphoma / complications,  pathology*,  virology
Child
DNA, Viral / analysis
Diagnosis, Differential
Disease-Free Survival
Follow-Up Studies
Herpesvirus 4, Human / genetics,  isolation & purification*
Humans
Immunohistochemistry
In Situ Hybridization
Male
Scapula / pathology*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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