Document Detail

Burkitt's lymphoma in pregnancy with bilateral breast involvement: case report with review of the literature.
MedLine Citation:
PMID:  20838063     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Burkitt's lymphoma (BL) in pregnancy presenting with breast involvement is a rare clinical entity, and only 13 cases have been reported so far.
CASE REPORT: We describe the case of a 28-year-old postpartum woman who presented with markedly enlarged breasts caused by BL. She was treated with 8 cycles of the CALGB 10002 regimen, as well as with irradiation to both breasts. After achieving a complete objective response, the patient received consolidation with high dose BEAM followed by autologous stem cell transplantation. 20 months after the initial diagnosis, our patient remains alive and relapse-free. Data extracted from the published case reports include information regarding demographic details, type of treatment, sites of disease, and survival. The clinical outcome of the reviewed cases was very unfavorable.
CONCLUSIONS: BL affecting breasts during pregnancy or lactation is a rare entity that requires a prompt diagnosis and an aggressive therapeutic approach.
Paraskevi Savvari; Chara Matsouka; Despoina Barbaroussi; Dimitrios Christoulas; Nikitas Nikitas; Meletios-A Dimopoulos; Christos A Papadimitriou
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-07-26
Journal Detail:
Title:  Onkologie     Volume:  33     ISSN:  1423-0240     ISO Abbreviation:  Onkologie     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-14     Completed Date:  2011-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7808556     Medline TA:  Onkologie     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  461-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Department of Clinical Therapeutics, University of Athens School of Medicine, Athens, Greece.
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MeSH Terms
Breast Neoplasms / diagnosis*,  therapy*
Burkitt Lymphoma / diagnosis*,  therapy*
Postpartum Period
Pregnancy Complications, Neoplastic / diagnosis*,  therapy*
Comment In:
Onkologie. 2010;33(8-9):419   [PMID:  20838055 ]

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