| Burden of malaria during pregnancy at the time of IPTp/SP implementation in Gabon. | |
| | |
MedLine Citation:
|
PMID: 20133992 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The new recommendations to prevent malaria in pregnant women have recently been implemented in Gabon. There is little information on the pregnancy indicators that are useful for their evaluation. A cross-sectional study for the assessment of the prevalence of peripheral, placental, and cord malaria and anemia among delivering women was performed at the largest public hospital of Gabon. Malaria prevalence was 34.4%, 53.6%, and 18.2% for maternal peripheral, placental, and cord blood respectively, with no difference between primigravidae and multigravidae. Submicroscopic infections were frequent and concerned all the positive cord samples. Maternal peripheral, late placental, and cord infections were all associated with a reduced mean birth weight in primigravidae (P = 0.02). Anemia prevalence was 53%, low birth rate was 13%, and prematurity was 25%. The use of intermittent preventive treatment with sulfadoxine-pyrimethamine (greater than or equal to one dose) combined with bed net was associated with a reduction in infection only in multigravidae and with a reduced risk of maternal anemia. |
| | |
Authors:
|
Marielle K Bouyou-Akotet; Solange Nzenze-Afene; Edgard B Ngoungou; Eric Kendjo; Mathieu Owono-Medang; Jean-Bernard Lekana-Douki; Ghislaine Obono-Obiang; Mathieu Mounanga; Maryvonne Kombila |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of tropical medicine and hygiene Volume: 82 ISSN: 1476-1645 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-02-05 Completed Date: 2010-03-02 Revised Date: 2011-07-22 |
Medline Journal Info:
|
Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
|
Languages: eng Pagination: 202-9 Citation Subset: AIM; IM |
Affiliation:
|
Department of Parasitology-Mycology and Tropical Medicine, Faculty of Medicine, Université des Sciences de la Santé, Libreville, Gabon. mariellebouyou@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Age Distribution Anemia / epidemiology Antimalarials / administration & dosage, therapeutic use Cross-Sectional Studies Drug Combinations Female Gabon / epidemiology Humans Malaria, Falciparum / epidemiology, parasitology* Mosquito Nets Odds Ratio Placenta / parasitology Pregnancy Pregnancy Complications, Hematologic / epidemiology Pregnancy Complications, Parasitic / epidemiology* Prevalence Pyrimethamine / administration & dosage*, therapeutic use* Risk Factors Sulfadoxine / administration & dosage*, therapeutic use* Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Antimalarials; 0/Drug Combinations; 2447-57-6/Sulfadoxine; 37338-39-9/sulfadoxine-pyrimethamine; 58-14-0/Pyrimethamine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Disentangling the effect of local and global spatial variation on a mosquito-borne infection in a ne...
Next Document: Evaluation of a rapid qualitative enzyme chromatographic test for glucose-6-phosphate dehydrogenase ...