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The Burden of Influenza B: A Structured Literature Review.
MedLine Citation:
PMID:  23327249     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We reviewed the epidemiology, clinical characteristics, disease severity, and economic burden of influenza B as reported in the peer-reviewed published literature. We used MEDLINE to perform a systematic literature review of peer-reviewed, English-language literature published between 1995 and 2010. Widely variable frequency data were reported. Clinical presentation of influenza B was similar to that of influenza A, although we observed conflicting reports. Influenza B-specific data on hospitalization rates, length of stay, and economic outcomes were limited but demonstrated that the burden of influenza B can be significant. The medical literature demonstrates that influenza B can pose a significant burden to the global population. The comprehensiveness and quality of reporting on influenza B, however, could be substantially improved. Few articles described complications. Additional data regarding the incidence, clinical burden, and economic impact of influenza B would augment our understanding of the disease and assist in vaccine development. (Am J Public Health. Published online ahead of print January 17, 2013: e1-e9. doi:10.2105/AJPH.2012.301137).
Authors:
W Paul Glezen; Jordana K Schmier; Carrie M Kuehn; Kellie J Ryan; John Oxford
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-17
Journal Detail:
Title:  American journal of public health     Volume:  -     ISSN:  1541-0048     ISO Abbreviation:  Am J Public Health     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1254074     Medline TA:  Am J Public Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
W. Paul Glezen is with the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX. Jordana K. Schmier is with Exponent Inc, Alexandria, VA. Carrie M. Kuehn is with Exponent Inc, Bellevue, WA. Kellie J. Ryan is with MedImmune, Gaithersburg, MD. John Oxford is with Bart's and the London Hospital, Queen Mary College, and Retroscreen Virology Ltd, London, UK.
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