Document Detail

Buprenorphine for the Treatment of Opioid Dependence in Pregnancy.
MedLine Citation:
PMID:  25062519     Owner:  NLM     Status:  Publisher    
The treatment of opioid dependence during pregnancy has historically consisted of either medication-assisted withdrawal or maintenance treatment with methadone. Buprenorphine maintenance treatment is emerging as a treatment during pregnancy with distinct benefits for the neonate and the pregnant woman. Buprenorphine is effective in decreasing the risk of relapse in pregnant women. In addition, prenatal use of buprenorphine appears to decrease the severity and duration of neonatal abstinence syndrome as compared with methadone maintenance. Management of buprenorphine includes initiation and maintenance treatment as well as careful planning for pain control during and after delivery and prevention of postpartum relapse risk. Only very small amounts of buprenorphine enter breast milk, making it a good option for those who elect to breast-feed. There is evidence that emerging collaborative care models are effective ways to deliver buprenorphine maintenance treatment, although more investigation is needed to generalize this to the obstetric setting.
Leena Mittal
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Publication Detail:
Journal Detail:
Title:  The Journal of perinatal & neonatal nursing     Volume:  28     ISSN:  1550-5073     ISO Abbreviation:  J Perinat Neonatal Nurs     Publication Date:    2014 July/September
Date Detail:
Created Date:  2014-7-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801387     Medline TA:  J Perinat Neonatal Nurs     Country:  -    
Other Details:
Languages:  ENG     Pagination:  178-184     Citation Subset:  -    
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