Document Detail


Bullous systemic lupus erythematosus--a case report and review.
MedLine Citation:
PMID:  8839001     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of a 20-year-old Chinese woman who presented with an 8-month history of a widespread pruritic blistering eruption. Histology, direct immunofluorescence and indirect immunofluorescence studies were consistent with bullous systemic lupus erythematosus (SLE). The lesions responded dramatically to dapsone 100 mg daily. Bullous SLE is a rare blistering condition with a distinctive combination of clinical, histologic and immunopathologic features that together constitute a unique bullous disease phenotype. The differential diagnoses and in particular the association between bullous SLE and epidermolysis bullosa acquisita are emphasized.
Authors:
Y K Tay; S N Wong; T Tan
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  24     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1997-02-04     Completed Date:  1997-02-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  879-82     Citation Subset:  IM    
Affiliation:
National Skin Centre, Singapore.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dapsone / therapeutic use
Dermatologic Agents / therapeutic use
Diagnosis, Differential
Epidermolysis Bullosa Acquisita / pathology
Female
Fluorescent Antibody Technique, Direct
Fluorescent Antibody Technique, Indirect
Humans
Lupus Erythematosus, Systemic / drug therapy,  pathology*
Phenotype
Pruritus / pathology
Skin Diseases, Vesiculobullous / drug therapy,  pathology*
Chemical
Reg. No./Substance:
0/Dermatologic Agents; 80-08-0/Dapsone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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