Document Detail

Bullous photosensitivity to naproxen: "pseudoporphyria".
MedLine Citation:
PMID:  2194465     Owner:  NLM     Status:  MEDLINE    
Pseudoporphyria is a photo-induced cutaneous bullous disease characterized by distinct clinical, histologic, and most recently, immunofluorescent features. By definition, results of porphyrin studies are normal in this disease. We describe here a woman with naproxen-induced pseudoporphyria, and we review previously reported cases of pseudoporphyria. The increasing frequency of pseudoporphyria is a result of the current popularity of nonsteroidal antiinflammatory drugs. Physicians need to be aware of this reversible skin disorder. Pseudoporphyria must be considered and an appropriate evaluation must be done when an individual who is taking nonsteroidal antiinflammatory drugs develops bullae and increased fragility of exposed skin.
S M Suarez; P R Cohen; V A DeLeo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  33     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-08-06     Completed Date:  1990-08-06     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  903-8     Citation Subset:  AIM; IM    
Department of Dermatology, Columbia-Presbyterian Medical Center, New York, NY 10032.
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MeSH Terms
Naproxen / adverse effects*
Photosensitivity Disorders / chemically induced*,  pathology
Porphyrias / chemically induced*,  pathology
Skin Diseases, Vesiculobullous / chemically induced*,  pathology
Reg. No./Substance:

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