| Bullous pemphigoid associated with Shy-Drager syndrome. | |
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MedLine Citation:
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PMID: 9714981 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a patient with Shy-Drager syndrome who developed multiple tense blisters mainly on the extremities. Circulating anti-basement membrane zone autoantibodies were detected by the indirect immunofluorescence method. Immunoblot analysis using normal human epidermal extracts demonstrated that this patient's serum reacted only with 230 kD bullous pemphigoid antigen (BPAG1). Concerning the pathoetiology of the association of bullous pemphigoid and Shy-Drager syndrome, we discuss a sequence similarity between BPAG1 and dystonin, a candidate gene for dystonia musculorum. |
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Authors:
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A Okazaki; T Iida; T Muramatsu; T Shirai; K Murata; T Takayanagi |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of dermatology Volume: 25 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 1998 Jul |
Date Detail:
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Created Date: 1998-09-09 Completed Date: 1998-09-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 465-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Nara Medical University, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autoantibodies
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analysis Autoantigens / genetics, immunology Basement Membrane / immunology Carrier Proteins / genetics, immunology Collagen* Cytoskeletal Proteins / genetics, immunology Epidermis / immunology Fluorescent Antibody Technique, Indirect Humans Immunoblotting Male Middle Aged Nerve Tissue Proteins / genetics, immunology Non-Fibrillar Collagens* Pemphigoid, Bullous / complications*, immunology Shy-Drager Syndrome / complications* |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Autoantigens; 0/Carrier Proteins; 0/Cytoskeletal Proteins; 0/DST protein, human; 0/Nerve Tissue Proteins; 0/Non-Fibrillar Collagens; 0/collagen type XVII; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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