Document Detail

Bullous lung disease due to marijuana.
MedLine Citation:
PMID:  18197922     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVE: In contrast to the well-described effects of tobacco smoking upon pulmonary emphysema, with approximately 15% of smokers being affected at the age of 65 years, the effects of marijuana smoking are rarely reported and poorly understood. METHODS: We report a series of 10 patients (mean age 41 +/- 9 years, eight male, two female), who presented over a period of 12 months to our respiratory unit with new respiratory symptoms, and who admitted to regular chronic marijuana smoking (>1 year continuously). Symptoms on presentation were dyspnoea (n = 4), pneumothorax (n = 4) and chest infection (n = 2). RESULTS: High-resolution CT revealed asymmetrical, variably sized, emphysematous bullae in the upper and mid zones. However, the CXR was normal in four patients and lung function was normal in five. CONCLUSIONS: Marijuana smoking leads to asymmetrical bullous disease, often in the setting of normal CXR and lung function. In subjects who smoke marijuana, these pathological changes occur at a younger age (approximately 20 years earlier) than in tobacco smokers.
Su W Hii; Jeff D C Tam; Bruce R Thompson; Matthew T Naughton
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Respirology (Carlton, Vic.)     Volume:  13     ISSN:  1440-1843     ISO Abbreviation:  Respirology     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-16     Completed Date:  2008-05-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9616368     Medline TA:  Respirology     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  122-7     Citation Subset:  IM    
Department of Allergy, Immunology and Respiratory Medicine, Monash University, Melbourne, Victoria, Australia.
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MeSH Terms
Cohort Studies
Dyspnea / etiology
Lung Diseases / etiology*,  pathology,  radiography*
Marijuana Smoking / adverse effects*
Middle Aged
Respiratory Function Tests
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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