Document Detail

Bulk laxative efficacy of a psyllium seed hydrocolloid and of a mixture of cellulose and pectin.
MedLine Citation:
PMID:  469025     Owner:  NLM     Status:  MEDLINE    
The cellulose/pectin combination (C/P) investigated in this study is as efficacious as a psyllium seed product widely used as a bulk laxative. Because of its physical characteristics (whiteness, lack of flavor and odor, lack of gelling upon standing), it is easy to use as a component of baked foods, sauces, drinks, stews, and in other recipes. Given its fecal bulking equivalence to the popular psyllium-based products, C/P offers advantages to the patient who takes a bulking agent regularly because of the wide choice of methods of consumption, ensuring better compliance over long periods of time. This cellulose/pectin combination appears to be a viable alternative to the limited choice presently available to the bulk laxative user and could also be used as a plant fiber supplement whenever this is desirable.
G A Spiller; E A Shipley; M C Chernoff; W C Cooper
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pharmacology     Volume:  19     ISSN:  0091-2700     ISO Abbreviation:  J Clin Pharmacol     Publication Date:    1979 May-Jun
Date Detail:
Created Date:  1979-10-17     Completed Date:  1979-10-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366372     Medline TA:  J Clin Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  313-20     Citation Subset:  IM    
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MeSH Terms
Cellulose / pharmacology*
Double-Blind Method
Feces / analysis
Gastrointestinal Motility
Middle Aged
Pectins / pharmacology*
Reg. No./Substance:
0/Cathartics; 0/Pectins; 8063-16-9/Psyllium; 9004-34-6/Cellulose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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