Document Detail

Building the posterior lateral line system in zebrafish.
MedLine Citation:
PMID:  21818862     Owner:  NLM     Status:  MEDLINE    
The posterior lateral line (pLL) in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate,morphogenesis, and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the pLL system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration, and self-organization of other organ systems during development and disease.
Ajay B Chitnis; Damian Dalle Nogare; Miho Matsuda
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Developmental neurobiology     Volume:  72     ISSN:  1932-846X     ISO Abbreviation:  Dev Neurobiol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-05-02     Completed Date:  2012-10-16     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  101300215     Medline TA:  Dev Neurobiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  234-55     Citation Subset:  IM    
The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
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MeSH Terms
Cell Movement / physiology
Lateral Line System / embryology*,  growth & development*,  metabolism
Morphogenesis / physiology
Receptors, Chemokine / biosynthesis
Signal Transduction / physiology
Zebrafish / embryology*,  growth & development*,  metabolism
Zebrafish Proteins / biosynthesis
Grant Support
Reg. No./Substance:
0/Receptors, Chemokine; 0/Zebrafish Proteins

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