| Building biologically active nucleic acid nanocomplexes. | |
| | |
MedLine Citation:
|
PMID: 18776236 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
The Bioplex technology allows the hybridization of functional entities to various forms of nucleic acids by the use of synthetic nucleic acid analogs. Such supramolecular assemblies can be made in a predetermined fashion and can confer new properties. The Zorro technology is based on a novel construct generated to simultaneously bind to both DNA strands. Such compounds may have gene silencing activity. |
| | |
Authors:
|
C I Edvard Smith; Karin E Lundin; Oscar E Simonson; Pedro M D Moreno; Mathias G Svahn; Malgorzata Wenska; Roger Strömberg |
Related Documents
:
|
18565736 - Viruses in acidic geothermal environments of the kamchatka peninsula. 14602906 - Nucleic acid binding properties of the nucleic acid chaperone domain of hepatitis delta... 2461336 - Distance analysis and sequence properties of functional domains in nucleic acids and pr... 15213806 - Preparation of endotoxin-free bacteriophages. 870286 - Helminthosporium speciferum as the cause of dermal and nasal maduromycosis in a cow. 12568596 - The development of a catalytic synthesis of münchnones: a simple four-component coupli... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Nucleic acids symposium series (2004) Volume: - ISSN: 1746-8272 ISO Abbreviation: Nucleic Acids Symp Ser (Oxf) Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-09-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101259965 Medline TA: Nucleic Acids Symp Ser (Oxf) Country: England |
Other Details:
|
Languages: eng Pagination: 27-8 Citation Subset: IM |
Affiliation:
|
Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital, 141 86 Huddinge, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: LNA incorporated siRNAs exhibit lower off-target effects compared to 2'-OMethoxy in cell phenotypic ...
Next Document: Recognizing and controlling biomolecules with "Smart" hybridization-based switches.