| Building Addressable Libraries: Amino-Acid Derived Fluorescent Linkers. | |
| | |
MedLine Citation:
|
PMID: 22229811 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
A new amino acid derived fluorescent linker for attaching molecules to the surface of a microelectrode array has been developed. Molecules to be monitored on an array are attached to the C-terminus of the linker, the N-terminus is then used to attach the linker to the array, and the sidechain is used to synthesize a fluorescent tag. The fluorescent group is made with a one-step oxidative cycloaddition reaction starting from a hydroxyindole group. The linker is compatible with site-selective Cu(I)-chemistry on the array, it allows for quality control assessment of the array itself, and it is compatible with the electrochemical impedance experiments used to monitor binding events on the surface of the array. |
| | |
Authors:
|
Takamasa Tanabe; Bo Bi; Libo Hu; Karl Maurer; Kevin D Moeller |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-9 |
Journal Detail:
|
Title: Langmuir : the ACS journal of surfaces and colloids Volume: - ISSN: 1520-5827 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9882736 Medline TA: Langmuir Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characterization of polyphenolic metabolites in the seeds of Vitis germplasm.
Next Document: Synthesis of Bishomoinositols and an Entry for Construction of a Substituted 3-oxabicyclo[3.3.1]-non...