| Brugada-like electrocardiographic pattern and ventricular fibrillation in a patient with primary hyperparathyroidism. | |
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MedLine Citation:
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PMID: 17344307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are several causes for ST segment abnormalities in leads V1 to V3. Hypercalcaemia and Brugada syndrome are among them. Both are known to produce ventricular arrhythmia, albeit only rare cases have been reported with documented evidence of ventricular arrhythmias in association with a hypercalcaemic crisis but none when hypercalcaemic coexists with Brugada syndrome. We describe a patient with primary hyperparathyroidism who presented with ventricular fibrillation, and the ECG showed changes similar to Brugada syndrome. The provocation test with flecainide was conducted twice. This was positive, both before and after parathyroidectomy when serum calcium and parathormone levels had normalized. The patient was treated for hypercalcaemia and underwent parathyroidectomy. This is the first report of oral flecainide test unmasking the diagnostic coved Brugada ECG pattern in a patient with primary hyperparathyroidism and raising attention to hypercalcaemia as a potential trigger for life-threatening arrhythmia in Brugada syndrome. |
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Authors:
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Lung-Sheng Wu; Chia-Tung Wu; Lung-An Hsu; Nazar Luqman; Chi-Tai Kuo |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology Volume: 9 ISSN: 1099-5129 ISO Abbreviation: Europace Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-03-08 Completed Date: 2007-08-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883649 Medline TA: Europace Country: England |
Other Details:
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Languages: eng Pagination: 172-4 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 199, Tunhwa N. Road, Taipei, Taiwan, Republic of, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brugada Syndrome
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etiology*,
physiopathology Electrocardiography Humans Hyperparathyroidism, Primary / complications*, physiopathology*, surgery Male Middle Aged Parathyroidectomy Ventricular Fibrillation / etiology*, physiopathology |
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