Document Detail

Brown tumor--a rare manifestation of renal osteodystrophy and severe secondary hyperparathyroidism: case report.
MedLine Citation:
PMID:  21462819     Owner:  NLM     Status:  In-Process    
Multifactorial disorders in mineral metabolism and bone structure occur early in the course of chronic kidney disease. The new term of 'chronic kidney disease--mineral and bone disorders' has been used to encompass a broad syndrome in which various abnormalities in bone and mineral metabolism are present in patients with chronic kidney disease. Brown tumors are an uncommon type of bone lesions that represent a focal manifestation of high-turnover bone disease. In our report, we describe a patient with chronic kidney disease on chronic hemodialysis that presented with multiple osseous lesions of the right elbow, right scapula and ribs. This case illustrates the importance of taking brown tumor in consideration in differential diagnosis and management of patients with an osseous mass and chronic kidney disease, where a failure to establish an accurate diagnosis can lead to unnecessary further diagnostic procedures and even extensive surgery, increasing the morbidity of these patients. Prevention, early diagnosis and treatment of secondary hyperparathyroidism are important in reducing the prevalence of high-turnover bone disease and consequential bone lesions including brown tumors.
Neven Barsić; Kresimir Cala; Drasko Pavlović
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta clinica Croatica     Volume:  49     ISSN:  0353-9466     ISO Abbreviation:  Acta Clin Croat     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-04-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9425483     Medline TA:  Acta Clin Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  299-304     Citation Subset:  IM    
Department of Gastroenterology, Sestre milosrdnice University Hospital, Zagreb, Croatia.
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