Document Detail


Brown tumor of the femur associated with double parathyroid adenomas.
MedLine Citation:
PMID:  15573206     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe parathyroid bone disease is a rare clinical presentation of primary hyperparathyroidism. Double parathyroid adenomas are even more rare cause of primary hyperparathyroidism. The authors present a case of double parathyroid adenomas in a 48-year-old man, who presented with painful left lower limb swelling, which was slowly growing in size in the last 20 years. Magnetic resonance imaging revealed a cystic bony lesion and coincidentally, a urinary bladder calculus. Biopsy of the mass revealed giant cell lesion. Laboratory investigations showed hypercalcemia and hypophosphatemia with elevated parathyroid hormone level. A computerized tomography scan of the neck delineated an adenoma of the left superior parathyroid gland, which was surgically removed. The left inferior parathyroid was also enlarged and was removed. Histological diagnosis confirmed double parathyroid adenomas. The rarity and the interesting clinical presentation of such association are discussed.
Authors:
Nidal A Younes; Waleed S Mahafza; Shukri S Agabi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  25     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-01     Completed Date:  2005-02-02     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  1701-3     Citation Subset:  IM    
Affiliation:
Department of Surgery, Faculty of Medicine, University of Jordan, PO Box 13024, Amman 11942, Jordan. niyounes@ju.edu.jo
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MeSH Terms
Descriptor/Qualifier:
Adenoma / diagnosis*,  pathology,  surgery
Bone Cysts / diagnosis*,  pathology,  surgery
Femoral Fractures / diagnosis,  pathology,  surgery
Femur* / pathology
Fractures, Spontaneous / diagnosis,  pathology,  surgery
Giant Cells / pathology
Humans
Hyperparathyroidism / diagnosis,  pathology,  surgery
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasms, Multiple Primary / diagnosis*,  pathology,  surgery
Parathyroid Neoplasms / diagnosis*,  pathology,  surgery
Parathyroidectomy
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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