Document Detail


Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
MedLine Citation:
PMID:  20358141     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax), with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two images ranged from -20 percent to +20 percent. Based on our observations, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.
Authors:
A R Hairil Rashmizal; A R Noraini; C Rossetti; N Abdul Jalil
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  51     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-04-01     Completed Date:  2010-07-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e37-9     Citation Subset:  IM    
Affiliation:
Discipline of Medical Radiations, School of Medical Sciences, Bundoora West Campus, Royal Melbourne Institute of Technology University, Bundoora, Victoria 3083, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue, Brown / metabolism,  radionuclide imaging*
Adult
Female
Fluorodeoxyglucose F18 / diagnostic use*
Humans
Positron-Emission Tomography / methods*
Tuberculosis, Lymph Node / radionuclide imaging
Chemical
Reg. No./Substance:
63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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