Document Detail


Brooke-Spiegler syndrome associated with cylindroma, trichoepithelioma, spiradenoma, and syringoma.
MedLine Citation:
PMID:  14739501     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Brooke-Spiegler syndrome is a rare, autosomally dominant disease characterized by the development of multiple cylindromas, trichoepitheliomas, and occasional spiradenomas. We report herein a case of Brooke-Spiegler syndrome in a 55-year-old woman associated with multiple cylindromas, spiradenomas, trichoepitheliomas, and syringomas that developed on her face. Her 52-year-old sister also suffered from multiple trichoepitheliomas. Although there is variable clinical and histological expression in Brooke-Spiegler syndrome, all of the tumors encountered in our case were related to folliculosebaceous-apocrine units.
Authors:
Koji Uede; Yuki Yamamoto; Fukumi Furukawa
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  31     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-01-23     Completed Date:  2004-05-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  32-8     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Wakayama Medical University, Wakayama, Japan.
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MeSH Terms
Descriptor/Qualifier:
Biopsy, Needle
Carcinoma, Adenoid Cystic / pathology*,  surgery
Carcinoma, Skin Appendage / pathology*,  surgery
Facial Neoplasms / pathology*,  surgery
Female
Hair Follicle / pathology
Humans
Immunohistochemistry
Middle Aged
Prognosis
Skin Neoplasms / pathology*,  surgery
Sweat Gland Neoplasms / pathology*,  surgery
Syndrome
Syringoma / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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