Document Detail

Bronchodilator responsiveness in a ventilator-dependent infant with severe tracheobronchomalacia.
MedLine Citation:
PMID:  10470578     Owner:  NLM     Status:  MEDLINE    
A neonatal case of severe, ventilator-dependent tracheobronchomalacia (TBM) is described. The extent of the malacic segment was determined by endoscopy and tracheobronchography. Additionally, relevant and ever increasing reversible peripheral airway obstruction was documented by measuring the mechanical properties of the respiratory system before and after salbutamol. With the combination of endoscopically guided aortopexy and salbutamol infusion, the infant was eventually weaned from mechanical ventilation at the age of 86 days. We speculate that in ventilator-dependent infants with severe TBM the determination of bronchodilator responsiveness may have clinical consequences.
B P Wagner; P Birrer; M Tönz; H Tschäppeler; J Pfenninger
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  25     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-11-04     Completed Date:  1999-11-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  729-32     Citation Subset:  IM    
Pediatric Intensive Care, Children's Hospital, University of Berne, Inselspital, Switzerland.
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MeSH Terms
Albuterol / pharmacology,  therapeutic use*
Bronchial Diseases / complications,  therapy*
Bronchodilator Agents / pharmacology,  therapeutic use*
Infant, Newborn
Positive-Pressure Respiration
Respiration, Artificial
Respiratory Distress Syndrome, Newborn / etiology,  therapy*
Respiratory Mechanics / drug effects*
Tracheal Diseases / complications,  therapy*
Reg. No./Substance:
0/Bronchodilator Agents; 18559-94-9/Albuterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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