Document Detail


Bronchoalveolar lavage in the diagnosis of pulmonary complications of bone marrow transplant patients.
MedLine Citation:
PMID:  10800066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bronchoalveolar lavage (BAL) has proved valuable in the diagnosis of pulmonary complications in immunosuppressed patients. We evaluated the diagnostic yield of BAL in pulmonary complications in bone marrow transplantation (BMT) recipients. We reviewed sequentially the records of 89 patients during an 18-month period. BAL was diagnostic in 42 patients (47%). The most common pulmonary complication diagnosed by BAL was diffuse alveolar hemorrhage (n = 15); followed by bacterial pneumonia (n = 10), respiratory syncytial virus (n = 8), aspergillosis (n = 6), Pneumocystis carinii pneumonia (n = 5), cytomegalovirus (CMV) (n = 4), and others (n = 4). The final diagnoses in the BAL non-diagnostic group were: bacterial pneumonia (n = 6), CMV (n = 6), idiopathic pneumonia syndrome (n = 5), cancer recurrence (n = 4), cardiogenic pulmonary edema (n = 4), and others (n = 9). We conclude that BAL is a useful diagnostic tool in BMT-related pulmonary complications.
Authors:
A J Huaringa; F J Leyva; J Signes-Costa; R C Morice; I Raad; A A Darwish; R E Champlin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bone marrow transplantation     Volume:  25     ISSN:  0268-3369     ISO Abbreviation:  Bone Marrow Transplant.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-13     Completed Date:  2000-06-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8702459     Medline TA:  Bone Marrow Transplant     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  975-9     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine Specialties, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
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MeSH Terms
Descriptor/Qualifier:
Bone Marrow Transplantation / adverse effects*
Bronchoalveolar Lavage*
Cross-Sectional Studies
Humans
Lung Diseases / diagnosis*,  etiology

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